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Effects of traditional Chinese medicine compounds for treating vitiligo on mushroom tyrosinase activity in vitro
In order to investigate the effect of traditional Chinese medicines (TCMs) on tyrosinase activity and provide experimental evidence for treating vitiligo, tyrosinase activity was estimated by measuring the rate of oxidation of DLúQ dopa. The findings showed that the tyrosinase activity increased in determining Vitilito Wan, Baibo Pian, Chaihu Shugan Tang and Baishi Wan(P< 0.01). While Vitiligo Wan components were tested, they all could activate the tyrosinase, and in orderof tyrosinase activity level increased they were Psoralea corylifolia L.(?°©¯×), Tribulus terrestris L.(¨ëã°òÔ ),Angelica sinensis(Oliv.) Diels(?? ) and Kochia scoparia(L.) Schrad(¦a?¤l). These data revealed that the levelsof tyrosinase activity were induced by Baibo Pian, Vitiligo Wan, Chaihu Shugan Tang, Baishi Wan, and Vitiligo Wancomponents.
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