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Traditional Chinese Medicine
Shenyi Center of Chinese Medicine Natural Patent Chinese Formulas |
| Ma Xing Zhi Ke Pian |
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Chinese name: Ma Hsing Chih Ke Pien (mah shing jih keh pyen) Ma Xing Zhi Ke Pian, mah sin chih ke Ephedra Apricot Stop Cough Tablets Ingredients Balloon flower root, Almond Kernel, Licorice root, Tangerine peel, Gypsum, Talcum, Honey Indications Cough, bronchitis, or asthma due to heat, fever, swollen lymph glands and sore throat Functions Clears lung heat, relieves asthma, resolves cough and phlegm, removes wind to clear the surface
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Ma Xing Zhi Ke Pian Medicine Researches Effect of ma-xin-shi-gan tang on the immune function in children with acute lower respiratory tract infection Yue Q, Ni ZY. Affiliated Hospital of Hubei College of TCM, Wuhan. This paper reported the effect of Ma-Xin-Shi-Gan tang (Decoction of Herba Ephedrae, Semen Armeniacae Amarum, Radix Glycyrrhizae and Gypsum Fibrosum) on the immune function of the children with acute lower respiratory tract infection (ALRTI). 64 cases of ALRTI children were chosen for clinical observation. Laboratory researches including 7 immune indexes: blood OKT3+ cell, OKT4+ cell, OKT8+ cell and OKT4+/OKT8+ cell ratio, serum IgG, IgA, IgM. Some tests in experimental mice were also made. The results showed: (1) Before treatment, the blood OKT3+ cell, OKT4+ cell and OKT4+/OKT8+ cell ratio of the ALRTI children were lower, OKT8+ cell was higher than that of the normal group, which indicated lowered function of cell mediated immunity (CMI) in ALRTI children. Furthermore, IgM content in serum of the ALRTI children was significantly higher than that of the normal group, which indicated a hyperhumoral immunity (HI). (2) Blood OKT4+ cell and OKT4+/OKT8+ cell ratio in children after treatment with the Decoction were higher than those before treatment, which suggested the Decoction can regulate the cell ratio of OKT4+ and OKT8+, and relieve the functional inhibition of CMI in ALRTI children, while comparing with the western medicine (WM) group, the blood OKT3+ cell, OKT4+ cell and serum IgG content in the Decoction group after treatment were higher. In the WM group, the serum IgG and IgA contents were lower than those of the normal group, which indicated inhibited function of HI after treatment. (3) In experimental mice, the Decoction can increase the phagocytic index of the macrophage, the spleen index and the level of serum hemolysin. It can also enhance the skin delayed allergic reaction of the mice. The effects of Ma-Xing-Gan-Shi-Tang on respiratory resistance and airway leukocyte infiltration in asthmatic guinea pigs. Author: Kao, S T : Yeh, T J : Hsieh, C C : Shiau, H B : Yeh, F T : Lin, J G Citation: Immunopharmacol-Immunotoxicol. 2001 Abstract: Ma-Xing-Gan-Shi-Tang (MXGST), a traditional Chinese medicine, has been used in treatment of the bronchial asthma for several centuries. However, the therapeutic mechanisms of this Chinese medicine are still far from clear. To understand the mechanism of anti-asthmatic property of MXGST, a guinea pig model of allergic asthma was used to investigate the effects of MXGST on Dermatophagoides pteronyssinus-induced early and late asthmatic responses and airway inflammation, and examine direct beta2-adrenoceptor agonist activity in guinea-pig isolated trachea. Administration of MXGST (10 g/kg) extracts significantly inhibited the antigen induced immediate asthmatic responses (IAR) in actively sensitized guinea pig. MXGST caused concentration-dependent relaxation in strips of guinea pig trachea contracted with carbachol, and ICI-118551, a selective beta2-adrenoceptor antagonist, significantly inhibit the relaxation caused by MXGST. Furthermore, examination of bronchoalveolar lavage fluid (BALF) revealed that MXGST significantly inhibited the increase in neutrophil in the airway at 1, 6 and 24 hr after antigen challenge. Histopathologic examination results showed that MXGST suppressed the neutrophil infiltration into lung tissue. In conclusion, we suggest that the anti-asthmatic effects of MXGST are mainly due to its stimulation of beta2-adrenoceptors on bronchial smooth muscle and its anti-inflammatory ability to inhibit the neutrophil into the airway. The precise mechanism of action of MXGST in asthma remains to be elucidated. This is the page of Chinese medicine for coughs, you can buy Ma Xing Zhi Ke Pian online here. |
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